| 세션명 | 대학원생 구두발표(토론II): 생체고분자 기반 의료공학 기술 |
|---|---|
| 발표장 | 제8-2회장 |
| 논문코드 | OD2-1 |
| 발표일 | 2024-04-3 |
| 발표시간 | 13:00-13:10 |
| 논문제목 | Antioxidative Impact of Phenolics-Loaded Nanocarriers on Cytoskeletal Network Remodeling of Invasive Cancer Cells |
| 발표자 | 정수희 |
| 발표자 소속 | 부산대학교 |
| 저자 | 정수희, 서성백† |
| 소속 | 부산대학교 |
| 논문초록 | Phenolic compounds of plants are known as possessing antioxidative properties. Even widely used in cosmetics and pharmaceuticals, the antioxidative effects of the phenolics on cellular behavior at molecular level remain unclear. This study explores the relationship of phenolic structure antioxidant activity. Analysis of various polyphenols revealed a correlation between the number of hydroxyl groups and antioxidant activity. Tannic acid (TA), with the highest number of hydroxyl groups, exhibits exceptional antioxidative capabilities and resistance to external stimuli. TA-loaded nano carriers effectively altered cytoskeletal networks, inhibiting cancer cell invasion. The study demonstrated the intricate relationship between phenolic structure, antioxidant efficacy, and their impact on cancer cell behaviors. This study offer a promising approach for antioxidation-functionalized drug delivery in diseases associated with oxidative stress. |
THE POLYMER SOCIETY OF KOREA